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NAPLEX在線考題,NAPLEX指南
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NAPLEX 考試由 250 道多選題組成,旨在測試安全有效的藥物實踐所需的知識、技能和能力。該考試涵蓋多個主題,包括藥理學、藥物治療學、藥物計算、藥物相互作用和患者諮詢。考生有六個小時完成試卷,該考試在美國及其領土的 Pearson VUE 考試中心以電子方式進行。NAPLEX 考試的及格分數為 75,未能一次通過考試的考生可以最多重複考試五次。
NAPLEX考試是一種衛生部藥物師執照考試,是一種基於電腦的考試,包括250個題目,涵蓋廣泛的與藥學相關的主題。該考試旨在測試候選人在藥理學、藥物治療、患者安全、藥物信息和藥學實踐管理等領域的知識和技能。該考試得分為0-150分,及格分數為75分。
NAPLEX考試被廣泛認為是世界上最具挑戰性的藥劑學考試之一。它要求考生具有藥理學,藥事法和藥事實踐方面的扎實基礎。考生還必須具備優秀的批判性思維和解決問題的能力,才能在這個考試中取得成功。
NAPLEX指南,NAPLEX真題材料
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最新的 NAPLEX Certification NAPLEX 免費考試真題 (Q149-Q154):
問題 #149
In the management of acute ischemic stroke, within how many minutes from symptom onset should alteplase be administered?
- A. 6 hours
- B. 24 hours
- C. 3 hours
- D. 12 hours
答案:C
解題說明:
Explanation
In the management of acute ischemic stroke, alteplase should be administered within 3 hours of symptom onset.
問題 #150
What is the Osmolarity of NS with KCL 40 meq/L? (MW of KCl: 74.55 g/mol) (MW of NaCl: 58.44 g/mol)
- A. 1108 mOsm/L
- B. 800 mOsm/L
- C. 388 mOsm/L
- D. 830 mOsm/L
- E. 308 mOm/L
答案:C
解題說明:
Explanation
KCl: Osmoles = number of particles in solution Convert 40meq to weight in g: 40meq * 1equiv/1000 mEq *
74.5g/1 equiv = 2.98g of KCL. Calculate mOsm/L: 2.98g/L * 1mol/74.5g * 2Osm/1 mol * 1000mOsm/1 Osm
= 80mOsm/L. NaCl: 0.9g/100ml * 1mol/58.5 g * 2 Osm/1mol * 1000 mOsm/ 1Osm * 1000ml/1L = 308 mOsm/L 80 mOsm/L + 308 mOsm/L = 388 mOsm/L
問題 #151
CJ is a 69-year-old male with a history of diabetes, hypertension and hypercholesterolemia. His fasting lipid profile is TC 530 mg/dL; LDL-C 125; HDL-C 48 mg/dL; and TG 640 mg/dL. His A1c 8.1, calculate creatinine clearance is 65mls/hr, BP 135/80 mm Hg, HR 70 beats /min.
His current medications include metformin 1000mg po bid, lisinopril 20mg daily, sitagliptin 50mg bid and atorvastatin 40mg daily.
What is the best pharmacological agent to initiate on CJ?
- A. Niacin 500mg twice daily
- B. Gemfibrozil 600mg twice daily
- C. Fenofibrate 162mg daily
- D. Increase atorvastatin to 80mg
- E. Fish oil 500mg twice daily
答案:C
解題說明:
It is reasonable to add triglyceride-lowering medications such as fibrates or niacin to prevent pancreatitis in those with triglyceride levels >500 mg/dL, which applies to this patient as his TG level is 640 mg/dL .
C. is wrong because gemfibrozil should not be initiated in patients on statin therapy because of an increased risk for muscle symptoms and rhabdomyolysis. Fenofibrate may be considered concomitantly with a low- or moderate- intensity statin when triglycerides are above 500 mg/dL,2, however he is on a high intensity statin therapy. For niacin, the IR dose should start at 100 mg TID2 and niacin does not lower triglyceride levels as much as fibrate do.4 Fenofibrates are dose adjusted for renal function lower than 60 mL/min to 54 mg/mL, so this dose is appropriate for this patient because of his renal function being above 60 mL/min. The best option is fenofibrate
162 mg daily, but this needs to be monitored for any symptoms of muscle pain exhibited by the patient, especially as the patient is at a higher risk due to being a diabetic. Fish oil is not a first line agent to treat hypertriglyceridemia.
Reference:
http://circ.ahajournals.org/content/129/25_suppl_2/S1
問題 #152
Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h.
How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80kg.
- A. 75 mL
- B. 15 mL
- C. 16.5 mL
- D. 18.75 mL
- E. 50 mL
答案:D
解題說明:
Explanation
80kg person = 15mg/kg/day = 1200mg/day 80mg /5ml = 1200mg/X X= 75mL/day / 4 doses = 18.75 mL per dose
問題 #153
All of the following may increase triglycerides except:
- A. Bile acid sequestrants
- B. Protease inhibitor
- C. Fish oil
- D. Oral estrogens
- E. Glucocorticoids
答案:C
解題說明:
Explanation
Agents that can cause elevated triglycerides: oral estrogens, glucocorticoids, bile acid sequestrants, protease inhibitors, retinoic acid, anabolic steroids, sirolimus, raloxifene, tamoxifen, beta blockers (not carvedilol), and thiazides.
問題 #154
......
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